In These Trial Designs

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Other potential out-of-pocket prices incurred to HCWs with CRI, akin to healthcare co-funds and direct non-medical prices (e.g. transport costs) had been excluded as no trial information was collected on these items. We utilized a choice analytic mannequin using Microsoft Excel to assemble a separate financial evaluation for each trial. Costs and well being outcomes were not discounted because the time horizon of the evaluation was less than one 12 months (28 days).

The primary outcome was the incremental value effectiveness ratio (ICER) per CRI case prevented. This was chosen as CRI in HCWs was the first endpoint in each trials (CRI instances in patients were not recorded). A one-means sensitivity evaluation was carried out on a variety of parameters to determine these that most considerably impacted on the ICER. For these causes, we calculated our ICER outcomes for this trial using the efficacy estimated for this ‘All N95’ arm

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